Enjoy the Collection of Newsletter Articles by Dr. Server Bozdogan to Participating Physicians.
This is Part 2 of our four-part series. We will examine how AIC Therapy targets the underlying mechanisms of Alzheimer’s and dementia, offering new ways to protect brain function. Part 3 will focus on Parkinson's, highlighting how AIC Therapy can help manage symptoms and slow disease progression.
Read MoreThis is the first part of our four-part series on how AIC Therapy can help prevent and manage neurodegenerative diseases. In this series, we look at how ionic calcium (AIC) therapy works on the cellular level to protect neurons, improve brain function, and support nerve repair for neurodegenerative diseases.
Read MoreIn cancer cells, calcium signaling is a critical regulator of metabolic processes that support cell survival. It specifically enhances the activity of TCA cycle enzymes, such as isocitrate dehydrogenase and oxoglutarate dehydrogenase, which are vital for producing the metabolic intermediates required for rapid proliferation. Beyond its metabolic support, calcium is essential for maintaining mitochondrial membrane potential and preventing apoptosis.
Read Moreregulates a wide array of cellular processes, including proliferation, cell death, migration, and immune response, which are crucial for cancer development. In recent decades, the disruption of Ca2+ homeostasis has been recognized as a critical factor in the initiation and progression of malignant diseases. Notably, Ca2+ also plays a pivotal role in modulating proto-oncogenes and tumor suppressor genes through intracellular signaling pathways.
Read MoreCancer cells thrive in an acidic microenvironment due to increased glycolysis and lactic acid production, known as the Warburg effect. This acidic environment promotes cancer cell invasion and metastasis. Anti-Orbital Ionic Calcium (AIC) therapy alters the microenvironment of cancer cells to be more alkaline, making the cancer cells more visible to the immune system.
Read MoreThe ability of calcium influx to disrupt the cell cycle and activate apoptosis pathways has highlighted calcium's potential in cancer treatment. However, the effects of calcium on cancer can only be realized through regulating cellular ionic calcium signaling, which can be achieved with Anti-orbital Ionic Calcium (AIC) therapy.
Read MoreStudies on leukemia treatment aim to target intracellular calcium levels, recognizing their crucial role in cancer cell behavior and survival. AIC-SG effectively targets these elevated calcium levels within leukemia cells, leading to their destruction of malignant cells and improving treatment outcomes.
Read MoreRegulated increases in cytosolic and organellar Ca2+ concentrations in lymphocytes control complex and crucial effector functions such as metabolism, proliferation, differentiation, antibody and cytokine secretion, cytotoxicity, apoptosis, and numerous gene transcriptions. AIC therapy restores calcium signaling, which is of paramount importance to proper immune function.
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