Correcting Dysregulated Immune Response by AIC in Various Autoimmune Diseases

Regulated increases in cytosolic and organellar Ca2+ concentrations in lymphocytes control complex and crucial effector functions such as metabolism, proliferation, differentiation, antibody and cytokine secretion, cytotoxicity, apoptosis, and numerous gene transcriptions. AIC therapy restores calcium signaling, which is of paramount importance to proper immune function.