AIC's Role in Modulating Tumor Pathways

Calcium ion (Ca2+) is a ubiquitous and versatile signaling molecule that regulates a wide array of cellular processes, including proliferation, cell death, migration, and immune response, which are crucial for cancer development. In recent decades, the disruption of Ca2+ homeostasis has been recognized as a critical factor in the initiation and progression of malignant diseases. Notably, Ca2+ also plays a pivotal role in modulating proto-oncogenes and tumor suppressor genes through intracellular signaling pathways.