Series on Oncology (Part3 of 4)

regulates a wide array of cellular processes, including proliferation, cell death, migration, and immune response, which are crucial for cancer development. In recent decades, the disruption of Ca2+ homeostasis has been recognized as a critical factor in the initiation and progression of malignant diseases. Notably, Ca2+ also plays a pivotal role in modulating proto-oncogenes and tumor suppressor genes through intracellular signaling pathways.

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Series on Oncology (Part 2 of 4)

Cancer cells thrive in an acidic microenvironment due to increased glycolysis and lactic acid production, known as the Warburg effect. This acidic environment promotes cancer cell invasion and metastasis. Anti-Orbital Ionic Calcium (AIC) therapy alters the microenvironment of cancer cells to be more alkaline, making the cancer cells more visible to the immune system.

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Series on Oncology (Part 1 of 4)

The ability of calcium influx to disrupt the cell cycle and activate apoptosis pathways has highlighted calcium's potential in cancer treatment. However, the effects of calcium on cancer can only be realized through regulating cellular ionic calcium signaling, which can be achieved with Anti-orbital Ionic Calcium (AIC) therapy.

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Ca+ll to Arms Against Leukemia

Studies on leukemia treatment aim to target intracellular calcium levels, recognizing their crucial role in cancer cell behavior and survival. AIC-SG effectively targets these elevated calcium levels within leukemia cells, leading to their destruction of malignant cells and improving treatment outcomes.

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Correcting Dysregulated Immune Response by AIC in Various Autoimmune Diseases

Regulated increases in cytosolic and organellar Ca2+ concentrations in lymphocytes control complex and crucial effector functions such as metabolism, proliferation, differentiation, antibody and cytokine secretion, cytotoxicity, apoptosis, and numerous gene transcriptions. AIC therapy restores calcium signaling, which is of paramount importance to proper immune function.

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